Cross-Frequency Coupling as a Unifying Pathophysiology for Brain Disorders

1-day workshop with Dirk de Ridder & Jay Gunkelman

presented at the Applied Neuroscience Society of Australasia Annual Conference 2017 , Canberra, Australia

Disclaimer! These recordings were made available by courtesy of the Applied Neuroscience Society of Australasia and Brain Mind & Memory Institute with a kind permission from presenters.

The brain can be considered as a ‘complex adaptive system’, analogous to the internet, economy or ant colonies, which permits us to constantly adjust to an ever changing environment, increasing our chances for survival and procreation. The brain functions as a Bayesian prediction machine, updating its predictions by active exploration of the environment through the senses. The information gathered in the environment results in a representation in the brain in the form of a perceptual pattern or network. Symptoms and diseases can be seen as maladaptive perceptions, thoughts or actions as a consequence of dysfunctional but stable networks (=attractor state).These pathological networks can be modulated by medication, but also by non-invasive and invasive neuromodulation.The workshop explains how based on this theory neurofeedback, infraslow network (sLORETA) neurofeedback, transcranial magnetic stimulation, and transcranial electrical stimulation (tDCS, tACS, tRNS) might influence these maladaptive symptom-generating networks.
After this workshop you should be able to:
-Understand how symptoms &diseases can be explained as emergent properties from maladaptive
brain networks
-How to evaluate these networks by analyzing an EEG (raw data, sLORETA, resting state and evoked brain
-activity, functional and effective connectivity)
-How neurofeedback exerts its effect on these networks
-How infraslow (<0.1 Hz) network neurofeedback works
-How brain stimulation influences these maladaptive networks.

About the Presenters:
Dirk de Ridder, Professor, Neurological Foundation Chair of Neurosurgery, Dunedin School of Medicine,
University of Otago, New Zealand.Founder and director of the BRAIĀ²N (Brain Research consortium for Advanced,
Innovative & Interdisciplinary Neuromodulation), Dirk’s main interest is the understanding and treatment of
phantom perceptions (sound, pain), especially by use of functional imaging navigated non-invasive
(TMS, tDCS, tACS, tRNS, LORETA neurofeedback) and invasive (implants) neuromodulation techniques. He has developed "burst" and "noise" stimulation as novel stimulation designs for implants, and is working on other stimulation designs.
Dirk has published 35 bookchapters, co-edited the Textbook of Tinnitus, and has authored/co-authored 221 papers(199Pubmed listed). He is reviewer for more than 60 journals.

Jay Gunkelman, QEEG Diplomate, is recognized as one of the leaders in the field of EEG and QEEG, and has processed over 500,000 EEGs since 1972. He has served as president of the iSNR, as well as a board member andtreasurer of the AAPB and is a past-president of the Biofeedback Society of California. Jay was the first EEG technologist to be certified in QEEG (1996) and was granted Diplomate status in 2002. He has conducted, published or participated in hundreds of research papers, articles, books and meetings internationally.
He lectures internationally on EEG/QEEG , on the topic of QEEG phenotype identification of neurological disorders. He has co-authored the text-book on EEG artifacting (2001). Jay remains busy with projects related to his seminal paper on EEG endophenotypes (2005, Clinical Electroencephalography). He is co-founder and Chief Science Officer of BrainScience International.


Part 1 Introduction:


















 
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